ObjectiveTo compare the clinical effects of endoscopic mucosal resection (EMR) with endoscopic submucosal dissection (ESD) in the treatment of patients with early gastric cancer. MethodsA total of 74 patients with early gastric cancer admitted to our hospital from January 2015 to July 2017 were selected and randomly divided into EMR group (35 cases) and ESD group (39 cases), and treated with EMR and ESD respectively. The operation duration, intraoperative bleeding volume, hospital stays, rate of complete resection of lesions, VAS score, postoperative complications and the prevalence of recurrence were compared between the two groups. ResultsCompared to the EMR group, the ESD group yielded less intraoperative bleeding volume, shorter hospital stay, significantly higher rate of complete resection of lesions (92.31% vs. 71.43%), and lower VAS score, with statistically significant differences (P＜0.05). There were no statistically significant differences in postoperative perforation and stenosis, as well as the recurrence rate 12 months after operation between the two groups (P＞0.05). ConclusionEmploying ESD in the treatment of early gastric cancer has certain advantages compared to EMR, which can reduce intraoperative bleeding volume, improve rate of complete resection of lesions, and alleviate the degree of pain in patients.

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