ObjectiveTo conduct logistic regression analysis of the factors affecting the severity of coronary artery disease in patients with acute ST-segment elevation myocardial infarction (STEMI), and to explore the correlation of white blood cell (WBC) counts to mean platelet volume (MPV) ratio (WMR) versus the degree of coronary artery stenosis in patients. MethodsA total of 191 STEMI patients undergoing PCI in the Affiliated Hospital of Guilin Medical University from December 2017 to May 2019 were selected as the research objects. The Gensini score was used to evaluate the severity of coronary artery disease. According to the results of the scores, the patients were divided into low score group (63 cases), median score group (62 cases), and high score group (66 cases). The general condition and laboratory examination results of the three groups were compared and analyzed, and the factors affecting the severity of coronary artery disease in STEMI patients were analyzed by logistic regression. ResultsThe WBC and WMR of patients in the high score group were significantly higher than those in the median and low score groups, and the differences were statistically significant (P＜0.05); the WBC and WMR of the median score group were higher than those of the low score group, but the differences were not statistically significant (P＞0.05). Logistic regression analysis results showed that WMR and FIB were independent factors influencing the severity of coronary artery disease in STEMI patients (P＜0.05). ConclusionWMR and WBC are closely related to the severity of coronary artery disease in STEMI patients, which are independent risk factors for the severity of coronary artery disease in STEMI patients.

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