ObjectiveTo observe the clinical efficacy of Jiedu Quyu Ditan decoction combined with chemotherapy in the treatment of patients with non-small cell lung cancer (NSCLC). MethodsA total of 120 NSCLC patients who were hospitalized in our department from January 2017 to December 2019 were selected, and they were divided into control group and observation group according to the sequence of visits, with 60 cases in each group. Patients in the control group were treated with gemcitabine and cisplatin following the chemotherapy plan, whereas patients in the observation group were treated with Jiedu Quyu Ditan decoction on the basic treatment of the control group, with 3 weeks as 1 treatment course, for 3 treatment courses in total. The short-term therapeutic effect and quality of life were compared between the two groups, and the Traditional Chinese Medicine (TCM) syndrome scores and tumor markers levels of the two groups were compared before and after treatment. ResultsThe observation group yielded a higher total effective rate of treatment (63.3% vs. 35.0%), and a higher improvement rate of life quality (65.0% vs. 41.7%) as compared with the control group, following statistically significant differences (P＜0.05). After 3 courses of treatment, the TCM syndrome scores, cytokeratin 19 fragment (CYFRA21-1), carbohydrate antigen 125 (CA125), neuron-specific enolase (NSE), carcinoembryonic antigen (CEA) of the two groups significantly decreased. The scores (levels) mentioned above of the observation group were significantly lower than those of the control group, and the differences were statistically significant (P＜0.05). ConclusionJiedu Quyu Ditan decoction combined with chemotherapy for treating patients with NSCLC can significantly improve the clinical therapeutic effect, significantly decrease the levels of tumor markers, and thus improve the quality of life in patients.

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