ObjectiveTo explore the risk factors for postpartum thyroiditis morbidity, and to provide references for preventing the occurrence of disease. MethodsA total of 54 patients with postpartum thyroiditis who were diagnosed and treated in the Maternal and Child Care Hospital of Guangxi Zhuang Autonomous Region from February 2019 to January 2020 were selected as the case group. According to 1 ∶1, 54 puerpera with matched age having parturition at the same time in the same hospital, who were required to have no underlying diseases, and postpartum thyroid function were normal, were selected as control group. Collecting clinical data of the two groups by reviewing the medical records. The levels of thyroid autoimmune antibodies (TRAb, TPOAb, TgAb), fasting blood glucose (FBG), blood lipids, 25-hydroxyvitamin D ［25(OH)D］, body mass index (BMI) were compared between the case group and the control group. Multivariate logistic regression analysis was performed on the risk factors for postpartum thyroiditis. ResultsThe univariate analysis results showed that the thyroid peroxidase antibody (TPOAb) level, the positive rate of thyroglobulin antibody (TgAb), and the incidence of 25(OH)D insufficiency/deficiency in patients with postpartum thyroiditis were significantly higher than those of the control group, following statistically significant differences (P＜0.05). Multivariate logistic regression analysis results showed that TgAb positive, TPOAb positive, and 25(OH)D insufficiency/deficiency were risk factors for the occurrence of postpartum thyroiditis. ConclusionTgAb positive, TPOAb positive, and 25(OH)D insufficiency/deficiency are closely related to the occurrence of postpartum thyroiditis. Supplementing vitamin D according to the test results may help to prevent the occurrence of postpartum thyroiditis.

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