ObjectiveTo explore the incidence and risk factors for cerebral microbleed in cerebral embolism patients with anticoagulation therapy. MethodsA total of 368 patients with acute cerebral embolism who were treated at the Second People′s Hospital of Foshan, Guangdong Province from September 2017 to September 2019 were selected as the research objects. The clinical data of the patients were retrospectively analyzed to explore the incidence of cerebral microbleed in cerebral embolism patients with anticoagulation therapy. The univariate and multivariate logistic regression analyses were performed to investigate the risk factors for cerebral microbleed in cerebral embolism patients with anticoagulation therapy. ResultsThe incidence of cerebral microbleed in cerebral embolism patients with anticoagulation therapy was 64.13%. The univariate analysis results showed that patients with cerebral embolism, with age ≥65 years old, a history of hypertension, blood glucose ≥8 mmol/L, NIHSS score ≥10 points, the existence of cerebral infarction lesions in CT examination, obtained a significantly higher incidence after anticoagulation therapy. The multivariate logistic regression analysis results showed that age ≥65 years old, hypertension, blood glucose ≥ 8 mmol/L, NIHSS ≥ 10 points, early cerebral infarction in CT examination in cerebral embolism patients were independent risk factors for cerebral microbleed in cerebral embolism patients with anticoagulation therapy. ConclusionThe incidence of cerebral microbleed is high in cerebral embolism patients with anticoagulation therapy. Age ≥65 years old, a history of hypertension, blood glucose ≥8 mmol/L, NIHSS ≥10 points, early cerebral infarction in CT examination are independent risk factors for cerebral microbleed in cerebral embolism patients with anticoagulation therapy.

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