ObjectiveTo explore the relationship between coagulation function and thyroid hormone levels in patients with hyperthyroidism complicated with atrial fibrillation. MethodsA total of 70 patients with hyperthyroidism complicated with atrial fibrillation (observation group) treated in our hospital from September 2018 to August 2019, along with 70 patients with simple hyperthyroidism (control group) also treated in our hospital during the same period were selected as the research objects. The levels of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thrombin time (TT), fibrinogen (FIB), activated partial thromboplastin time (APTT), prothrombin time (PT) were detected and compared between the two groups. Pearson correlation analysis was performed on the relationship between the coagulation function indicators levels and the thyroid hormone levels in patients with hyperthyroidism complicated with atrial fibrillation. ResultsThere were no statistically significant differences in the levels of TSH, FT3, and FT4 between the two groups (P＞0.05). The PT level of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P＜0.05). There were no statistically significant differences in the levels of TT, FIB, and APTT between the two groups (P＞0.05). The APTT of patients with hyperthyroidism complicated with atrial fibrillation was negatively correlated with FT3 and FT4 (r=-0.223, r=-0.250). ConclusionThe blood of patients with hyperthyroidism complicated with atrial fibrillation is in a state of hypercoagulability, and the differences between coagulation function and thyroid hormone levels in the above-mentioned patients are not significant as compared with those with simple hyperthyroidism. There is no significant correlation between the coagulation indexes levels and thyroid hormone levels in patients.

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