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不同血糖水平控制状况对妊娠糖尿病患者胎盘钙化、脐动脉血流动力学及分娩结局的影响▲
Effect of different control statuses of blood glucose levels on placental calcification, umbilical artery hemodynamics and delivery outcome in patients with gestational diabetes

内科 202116卷01期 页码:15-17

作者机构:偃师市人民医院产一科,河南省洛阳市471900

基金信息:▲基金项目:2019年度河南省医学科技攻关计划推广项目(LHGJ20190398)

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2021.01.05

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目的探讨不同血糖水平控制状况对妊娠糖尿病患者胎盘钙化、脐动脉血流动力学及分娩结局的影响。方法回顾性分析2017年1月至2019年8月在我院接受治疗的148例妊娠糖尿病患者的临床资料,根据患者的血糖控制状况,将患者分为血糖控制良好组(85例)和血糖控制不良组(63例),比较两组患者的胎盘钙化情况、脐动脉血流动力学检测结果以及不良妊娠结局的发生情况。结果血糖控制良好组患者的胎盘钙化发生率(7.1%)显著低于血糖控制不良组患者(20.6%),差异有统计学意义(P<0.05)。血糖控制良好组患者的胎儿脐动脉阻力指数(RI)、胎儿脐动脉收缩压与舒张压比值(S/D)明显低于血糖控制不良组患者,不良妊娠结局的发生率(8.8%)明显低于血糖控制不良组患者(20.6%),差异有统计学意义(P<0.05)。结论妊娠糖尿病患者血糖水平控制不良可导致胎盘钙化、脐动脉血流动力学发生改变,显著增加不良妊娠结局的发生风险,必须采取适当的措施进行干预。
ObjectiveTo explore the influence of different control statuses of blood glucose levels on placental calcification, umbilical artery hemodynamics and delivery outcome in patients with gestational diabetes. MethodsA retrospective analysis of the clinical data was conducted on 148 patients with gestational diabetes who were treated in our hospital from January 2017 to August 2019. The patients were divided into well-controlled blood glucose group (85 cases) and poorly-controlled blood glucose group (63 cases) according to the control statuses of blood glucose in patients. The placental calcification, test results of umbilical artery hemodynamic and the occurrence of adverse pregnancy outcomes were compared between the two groups. ResultsThe incidence of placental calcification (7.1%) in the well-controlled blood glucose group was significantly lower than that in the poorly-controlled blood glucose group (20.6%), and the difference was statistically significant (P<0.05). The fetal umbilical artery resistance index (RI) and the ratio of fetal umbilical artery systolic blood pressure to diastolic blood pressure (S/D) in the well-controlled blood glucose group were significantly lower than those in the poorly-controlled blood glucose group, and the incidence of adverse pregnancy outcomes (8.8%) was significantly lower than that in the poorly-controlled blood glucose group (20.6%), the differences were statistically significant (P<0.05). ConclusionPoor control of blood glucose levels in patients with gestational diabetes can lead to placental calcification and changes of umbilical artery hemodynamics, and significantly increase the risk of adverse pregnancy outcomes, so that appropriate measures must be taken for intervention.

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