Effect of different control statuses of blood glucose levels on placental calcification, umbilical artery hemodynamics and delivery outcome in patients with gestational diabetes
ObjectiveTo explore the influence of different control statuses of blood glucose levels on placental calcification, umbilical artery hemodynamics and delivery outcome in patients with gestational diabetes. MethodsA retrospective analysis of the clinical data was conducted on 148 patients with gestational diabetes who were treated in our hospital from January 2017 to August 2019. The patients were divided into well-controlled blood glucose group (85 cases) and poorly-controlled blood glucose group (63 cases) according to the control statuses of blood glucose in patients. The placental calcification, test results of umbilical artery hemodynamic and the occurrence of adverse pregnancy outcomes were compared between the two groups. ResultsThe incidence of placental calcification (7.1%) in the well-controlled blood glucose group was significantly lower than that in the poorly-controlled blood glucose group (20.6%), and the difference was statistically significant (P<0.05). The fetal umbilical artery resistance index (RI) and the ratio of fetal umbilical artery systolic blood pressure to diastolic blood pressure (S/D) in the well-controlled blood glucose group were significantly lower than those in the poorly-controlled blood glucose group, and the incidence of adverse pregnancy outcomes (8.8%) was significantly lower than that in the poorly-controlled blood glucose group (20.6%), the differences were statistically significant (P<0.05). ConclusionPoor control of blood glucose levels in patients with gestational diabetes can lead to placental calcification and changes of umbilical artery hemodynamics, and significantly increase the risk of adverse pregnancy outcomes, so that appropriate measures must be taken for intervention.