目的分析急性脑梗死(ACI)患者支架取栓术后出血转化的影响因素。方法回顾性分析2018年3月至2020年3月在我院行支架取栓术治疗的76例ACI患者的临床资料,按术后是否出现出血转化将患者分为未出血转化组(57例)和出血转化组(19例)。比较两组患者的性别、年龄、既往病史等一般资料以及各项实验室检测指标水平;对ACI患者支架取栓术后发生出血转化的危险因素进行多因素Logistic回归分析。结果两组患者的吸烟史、饮酒史、高脂血症、心房颤动、大面积脑梗死、美国国立卫生研究院卒中量表(NIHSS)评分以及空腹血糖(FBG)水平、低密度脂蛋白胆固醇(LDL-C)水平等情况比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,心房颤动、大面积脑梗死、高NIHSS评分、高FBG水平、高LDL-C水平是ACI患者支架取栓术后发生出血转化的独立危险因素(P<0.05)。结论心房颤动、大面积脑梗死、高NIHSS评分以及高FBG、高LDL-C水平是ACI患者支架取栓术后发生出血转化的独立危险因素。
ObjectiveTo analyze the influencing factors of hemorrhagic transformation in patients with acute cerebral infarction (ACI) after stent thrombectomy. MethodsA retrospective analysis of the clinical data of 76 ACI patients who underwent stent thrombectomy in our hospital from March 2018 to March 2020 was conducted, and the patients were divided into non-hemorrhagic transformation group (57 cases) and hemorrhagic transformation group (19 cases) according to the presence of hemorrhagic transformation occurrence after surgery. The gender, age, past medical history and other levels of various laboratory test indicators as well were compared between the two groups. Multivariate logistic regression analysis was performed on the risk factors of hemorrhagic transformation after stent thrombectomy in ACI patients. ResultsThere were statistically significant differences in the history of smoking and drinking, hyperlipidemia, atrial fibrillation, large-area cerebral infarction, National Institutes of Health Stroke Scale (NIHSS) score, fasting blood glucose (FBG) level, low-density lipoprotein cholesterol (LDL-C) level, etc. (P<0.05). The results of multivariate logistic regression analysis showed that atrial fibrillation, large-area cerebral infarction, high NIHSS score, high FBG level, and high LDL-C level were independent risk factors for hemorrhagic transformation after stent thrombectomy in ACI patients (P<0.05). ConclusionAtrial fibrillation, large-area cerebral infarction, high NIHSS score, high FBG and LDL-C levels are independent risk factors for hemorrhagic transformation after stent thrombectomy in ACI patients.