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银丹心脑通软胶囊治疗慢性稳定型心绞痛合并高脂血症患者临床效果观察▲
Yindan Xinnaotong soft capsule in treating patients with chronic stable angina pectoris complicated with hyperlipidemia: an observation on the clinical effect

内科 202116卷02期 页码:153-155+192

作者机构:郑州市第九人民医院心血管内科二病区,河南省郑州市450000

基金信息:▲基金项目:河南省医学科技攻关计划项目(201702333)

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2021.02.06

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目的探讨银丹心脑通软胶囊治疗对慢性稳定型心绞痛(SAP)合并高脂血症患者血脂水平和心绞痛发作情况的影响。方法选取2019年1月至2020年5月在我院治疗的SAP合并高脂血症患者202例,采用随机数字法分为两组,每组101例。对照组患者给予常规治疗,观察组患者在常规治疗的基础上加用银丹心脑通软胶囊治疗。比较两组患者治疗前后的血脂水平、心绞痛发作情况和治疗期间的不良反应发生情况。结果治疗8周后,观察组患者的TG、TC、LDL-C水平显著低于对照组,HDL-C水平显著高于对照组,差异有统计学意义(P<0.05);观察组患者每周的心绞痛发作次数显著少于对照组,每次发作的持续时间也显著短于对照组,差异有统计学意义(P<0.05)。治疗期间两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论在常规治疗的基础上,加用银丹心脑通软胶囊治疗可显著改善SAP合并高脂血症患者的血脂代谢状况,降低患者心绞痛发作频率,缩短每次发作持续时间,治疗安全性高,有利于改善患者病情。
ObjectiveTo investigate the effect of Yindan Xinnaotong soft capsule on blood lipid level and anginal frequency in patients with chronic stable angina pectoris (SAP) complicated with hyperlipidemia. MethodsA total of 202 SAP patients complicated with hyperlipidemia who were treated in our hospital from January 2019 to May 2020 were selected and divided into two groups by the random number method, with 101 cases in each group. Patients in the control group were given conventional treatment, based on which patients in the observation group were additionally administrated with Yindan Xinnaotong soft capsule. The blood lipid levels and the onset of anginal frequency before and after treatment, as well as the occurrence of adverse reactions during the treatment were compared between the two groups. ResultsAfter 8 weeks of treatment, the levels of TG, TC, and LDL-C in the observation group were significantly lower than those in the control group, and the HDL-C level was significantly higher than that in the control group, with statistically significant differences (P<0.05). The times of anginal frequency per week and duration of each frequency in the observation group were significantly less or shorter than those in the control group, with statistically significant differences (P<0.05). During the treatment, there was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). ConclusionOn the basis of conventional treatment, additionally administrating Yindan Xinnaotong soft capsule can significantly improve the blood lipid metabolism of SAP patients complicated with hyperlipidemia, reduce the anginal frequency, shorten the duration of each frequency, with a high safety of treatment, and it is also helpful to improve the disease condition in patients.

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