内科

目的探讨复方红衣补血口服液辅治妊娠期缺铁性贫血（IDA）患者的疗效及对铁代谢、红细胞的影响。方法选取2019年3月至2020年3月我院收治的妊娠期IDA患者108例为研究对象，采用信封法分为对照组与联合组，每组54例。对照组患者给予乳酸亚铁治疗，联合组患者给予乳酸亚铁及复方红衣补血口服液治疗，疗程4周。比较两组患者治疗前后的铁代谢、血细胞变化情况；比较两组患者的疗效及治疗期间的不良反应发生情况。结果治疗4周，联合组患者的治疗总有效率（98.2%）显著高于对照组（85.2%），疗效明显优于对照组，差异有统计学意义（P＜0.05）。治疗前，两组患者的血清铁（SI）、血清铁蛋白（SF）、转铁蛋白饱和度（TSAT）、血红蛋白（Hb）、红细胞比容（HCT）、平均红细胞体积（MCV）水平比较，差异均无统计学意义（P＜0.05）；治疗4周后，两组患者的SI、SF、TSAT、Hb、HCT、MCV水平均明显升高，联合组患者的水平显著高于对照组，差异有统计学意义（P＜0.05）。治疗期间，两组患者的不良反应发生率比较差异无统计学意义（P＞0.05）。结论乳酸亚铁联合复方红衣补血口服液治疗妊娠期缺铁性贫血患者临床效果确切，可显著改善铁代谢状况，促进红细胞功能恢复，治疗安全性良好。

ObjectiveTo explore the curative effect of compound Hongyi Buxue oral liquid assisted in treating patients with iron deficiency anemia (IDA) during pregnancy and its influence on iron metabolism and red blood cells. MethodA total of 108 IDA patients during pregnancy admitted to our hospital were selected as the research objects, and they were divided into control group and combination group by the envelope method, with 54 cases in each group. Patients in the control group were treated with ferrous lactate, and patients in the combination group were treated with ferrous lactate and compound Hongyi Buxue oral liquid, for a 4-week treatment course. The iron metabolism and blood cell changes of the two groups were compared before and after treatment; meanwhile, the efficacy and the adverse reactions during the treatment were also compared between the two groups. ResultsAfter 4 weeks of treatment, the total effective rate of the combination group (98.2%) was significantly higher than that of the control group (85.2%), and the curative effect was significantly superior to that of the control group, with statistically significant differences (P＜0.05). There were no statistically significant differences in the levels of serum iron (SI), serum ferritin (SF), transferrin saturation (TSAT), hemoglobin (Hb), hematocrit (HCT), and mean corpuscular volume (MCV) between the two groups (P＜0.05). After 4 weeks of treatment, the levels mentioned above significantly increased, and the combination group yielded higher levels as compared with the control group, with statistically significant differences (P＜0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups during the treatment period (P＞0.05). ConclusionFerrous lactate combined with compound Hongyi Buxue oral liquid has a definite clinical effect in the treatment of IDA patients during pregnancy, which can significantly improve iron metabolism, promote the recovery of red blood cell functions, and thus it has a good treatment safety.