ObjectiveTo explore the influences of body mass index (BMI) on the related indexes and pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in infertility patients with polycystic ovary syndrome (PCOS). MethodsThe clinical data of 230 PCOS patients received IVF-ET as assisted reproduction were retrospectively analyzed, and they were assigned to three groups according to BMI, namely normal weight group (18.5 kg/m2≤BMI＜24 kg/m2), overweight group (24 kg/m2≤BMI<28 kg/m2), obesity group (BMI≥28 kg/m2). The ovulation-induction-related indicators and pregnancy outcomes of the three groups were compared. ResultsThere were no statistically significant differences in the total Gn dosage, Gn duration, oocyte retrieval rate and cleavage rate between the three groups (P＞0.05). There were statistically significant differences in the HCG trigger daily E2 level, the occurrence rate of moderate-severe ovarian hyperstimulation syndrome and the optimal embryo rate between the three groups (P＜0.05). There were statistically significant differences in the rates of pregnancy and miscarriage, the incidence of gestational diabetes and the incidence of macrosomia between the three groups (P＜0.05). ConclusionBMI can cause seriously bad influences on PCOS patients received IVF-ET as assisted reproduction, patients with higher BMI obtain lower quality of ovum and fertility, whereas higher incidence of adverse pregnancy outcomes. Therefore, strict weight control may prominently improve the effects of IVF-ET as assisted reproduction in patients with PCOS.

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