ObjectiveTo observe the clinical effects of oxiracetam combined with repeated transcranial magnetic stimulation (rTMS) on patients with vascular dementia (VD) after cerebral infarction. MethodsA total of 120 patients with VD after cerebral infarction treated in our hospital from January 2018 to January 2020 were selected as the research objects, and they were divided into observation group and control group according to the random number method, with 60 cases in each group. The control group was treated with oxiracetam, while the observation group was treated with repeated transcranial magnetic stimulation on the basis of the control group, with 21 days as a course of treatment and 3 treatment courses for both groups. The cognitive function, neurological function, self-care ability and hemodynamic status of common carotid artery were detected and compared between the two groups before and after treatment. ResultsBefore treatment, there were no statistically significant differences in the scores of mini mental state examination (MMSE) and montreal cognitive assessment (MoCA) between the two groups (P＞0.05). After 3 courses of treatment, the MMSE score and MoCA score of patients in the observation group were significantly higher than those of the control group, with statistically significant differences (P＜0.05). Before treatment, there were no statistically significant differences in national institute of health stroke scale (NIHSS) score and modified Barthel index (MBI) score between the two groups (P＞0.05). After 3 courses of treatment, the NIHSS score of the observation group was significantly lower than that of the control group, and the MBI score was significantly higher than that of the control group, with statistically significant differences (P＜0.05). Before treatment, there were no statistically significant differences in blood flow velocity, blood flow and vascular resistance of common carotid artery between the two groups (P＞0.05). After 3 courses of treatment, the blood flow velocity and blood flow of the common carotid artery in the observation group were significantly higher than those in the control group, and the vascular resistance was significantly lower than that in the control group, with statistically significant differences (P＜0.05). ConclusionOxiracetam combined with rTMS can significantly improve the common carotid artery hemodynamic status of patients with VD after cerebral infarction, effectively restore the neurological function of patients, and improve the cognitive function and self-care ability of patients.

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