目的探讨中西医结合治疗类风湿关节炎(RA)的临床疗效。方法将我院门诊及住院部收治的64例RA患者随机分为两组,其中对照组32例给予甲氨蝶呤片、柳氮磺吡啶片、双氯芬酸钠肠溶片治疗,观察组32例在此基础上应用中药薏苡仁汤加减口服治疗,两组患者均在用药12周后进行疗效评价。结果观察组疗效优于对照组,两组比较差异有统计学意义(P<0.05);与治疗前相比,两组患者晨僵持续时间、关节肿胀数目、关节压痛数目及血沉(ESP)、C反应蛋白(CRP)、类风湿因子(RF)均较治疗前有明显改善(P<0.05),与对照组相比,观察组除ESP、RF外其他指标改善更为明显(P<0.05)。结论中西医结合治疗RA疗效确切,能明显改善患者病情、提高生活质量。
ObjectiveTo investigate clinical effect of integrated Chinese medicine and western medicine on patients with rheumatoid arthritis. Methods64 patients with rheumatoid arthritis were randomly and equally divided into two groups (the control group and the observation group). The two groups were all treated with methotrexate tablets, sulfasalazine tablets and diclofenac sodium enteric-coated tablets while the modified Yiyiren decotion was given to the observation group. The curative effect of the two groups were evaluated after 12-week treatment. ResultsThe effect of the observation group was higher than that of the control group, indicating that there was a significant difference between the two groups(P<0.05). Morning stiffness, swollen joints, joint tenderness, ESP, CRP, and RF in the two groups were significantly improved (P<0.05) after the treatment. All the indicators above in the observation group were improved more obviously than those in the control group except RF and ESP (P<0.05). ConclusionIntegrated Chinese medicine and western medicine is effective and safe in the treatment of RA, which can significantly improve patients’ condition and their life quality.