目的分析维持性血液透析(MHD)患者的干体重控制情况及其影响因素。方法选取2018年7月至2021年1月在我院进行MHD治疗的患者280例为研究对象。采用人体成分分析仪测量患者干体重,测量患者透析前、透析1个月后的体重,计算患者透析前后体重差值的绝对值占干体重的比例,根据此比例将280例MHD患者分为干体重控制严格组和干体重控制非严格组,对影响患者干体重控制效果的因素进行单因素及多因素logistic回归分析。结果单因素分析结果显示,干体重控制严格组患者的糖尿病史、平均每日食盐摄入量、平均每日水摄入量、平均每日残余尿量、白蛋白(ALB)水平、NT-proBNP水平与干体重控制非严格组患者比较,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,糖尿病史、平均每日食盐摄入量过多、平均每日水摄入量过多、ALB水平过低是影响MHD患者干体重控制不严格的独立危险因素。结论维持性血液透析患者干体重控制不严格的情况常有发生,糖尿病史、每日食盐摄入量过多、每日水摄入量过多、白蛋白水平过低是影响患者干体重控制不严格的独立危险因素。
ObjectiveTo analyze the situations of dry weight control and its influencing factors in maintenance hemodialysis (MHD) patients. MethodsA total of 280 patients receiving maintenance hemodialysis treatment in our hospital from July 2018 to January 2021 were enrolled as the research objects. The dry weight of patients were measured by body composition analyzer, and the weight of patients before and after dialysis for 1 month were measured. The ratio of absolute value of weight difference before and after dialysis to dry weight was calculated. According to this ratio, 280 MHD patients were divided into strict dry weight control group and non-strict dry weight control group. Univariate and multivariate logistic regression analysis were performed on factors affecting the effect of dry weight control. ResultsUnivariate analysis results showed that there were statistically significant differences in diabetes history, average daily salt intake, average daily water intake, average daily residual urine volume, albumin (ALB) and NT-proBNP levels between strict dry weight control group and non-strict dry weight control group (P<0.05). The results of multivariate logistic regression analysis showed that diabetes history, excessive average daily salt intake, excessive average daily water intake, and low ALB level were independent risk factors that affecting the poor control of dry weight in MHD patients. ConclusionPoor control of dry weight often occurs in MHD patients, diabetes history, excessive daily salt intake, excessive daily water intake and low ALB level are independent risk factors that affecting the poor control of dry weight.