ObjectiveTo investigate the clinical effect of microecological regulators combined with antibiotics in the treatment of children with bacterial diarrhea. MethodsA total of 66 children with bacterial diarrhea were enrolled as research subjects and randomly divided into a control group or a test group, with 33 cases in each group. The children in the control group were treated with routine antibiotics, based on which the children in the test group were treated with microecological regulators additionally. Both groups received treatment for 1 week. The followings were compared between the two groups, including the clinical efficacy and the peripheral blood procalcitonin (PCT), C-reactive protein (CRP), and white blood cell count levels after the 1-week treatment. The time to defervescence, time to vomiting relief, time to abdominal pain relief, time to normal stool test results, hospital stay, time for diarrhea, total course of diarrhea, the frequency of defection on the 3rd and 6th days of treatment, and parents′ satisfaction were recorded and compared. ResultsBefore the treatment, there was no significant difference in the peripheral blood PCT, CRP, or white blood cell count level between the two groups (all P＞0.05). After the 1-week treatment, the test group had lower peripheral blood PCT, CRP, and white blood cell count levels, a higher total effective rate, shorter time to defervescence, time to vomiting relief, time to abdominal pain relief, time to normal stool test results, hospital stay, time for diarrhea, and total course of diarrhea, less defection frequency on the 3rd and 6th days of the treatment, and higher parents′ satisfaction as compared with the control group (all P＜0.05). ConclusionThe combination of microecological regulators and antibiotics achieves superior efficacy in the treatment of children bacterial diarrhea, which can effectively reduce children’s inflammatory factors levels, shorten the disease course, decrease the defection frequency, and obtain high satisfaction of parents.

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