内科

目的观察常规西药联合归芍柔筋汤+中医理疗治疗肝血亏虚型帕金森病的临床效果。方法选取48例肝血亏虚型帕金森病患者作为研究对象，将其随机分为治疗组（25例）和对照组（23例）。对照组患者行常规西药治疗，治疗组患者在对照组的基础上加用归芍柔筋汤联合中医理疗治疗，两组患者均治疗3周。比较治疗前后两组患者的中医证候积分、帕金森综合评分量表（UPDRS）评分，治疗总有效率和治疗期间不良反应发生情况。结果治疗前，两组患者各方面中医症候积分比较，差异均无统计学意义（均P＞0.05）；治疗3周后，治疗组患者肢体颤振、项背僵直、行走不稳、活动减少、舌象、脉象方面的中医症候积分均低于对照组（均P＜0.05）。治疗3周后，治疗组患者的治疗总有效率（96.00%）高于对照组（69.67%）（P＜0.05）。治疗前，两组患者UPDRS总分及其各维度评分比较，差异均无统计学意义（均P＞0.05）；治疗3周后，治疗组患者UPDRS总分及其各维度评分均低于对照组（均P＜0.05）。两组患者治疗期间的不良反应发生率差异无统计学意义（P＞0.05）。结论常规西药联合归芍柔筋汤+中医理疗治疗肝血亏虚型帕金森病，可以有效地改善患者的临床症状，临床疗效明显，且不增加不良反应。

ObjectiveTo observe the clinical effect of conventional western medicine combined with Guishao Roujing decoction + traditional Chinese medicine physical therapy in the treatment of Parkinson′s disease with liver blood deficiency pattern. MethodsA total of 48 Parkinson′s disease patients with liver blood deficiency pattern were selected as research subjects and randomly divided into a treatment group (25 cases) or a control group (23 cases). The control group patients were treated with conventional western medicine, based on which the treatment group patients were treated with Guishao Roujing decoction combined with traditional Chinese medicine physical therapy additionally. Both groups were treated for 3 weeks. The followings were compared between the two groups, including Chinese Medical Syndrome Score and United Parkinson Disease Rate Scale (UPDRS) score before and after the treatment, the total effective rate after the treatment, and the occurrence of adverse reactions during the treatment. ResultsBefore the treatment, there was no significant difference in Chinese Medical Syndrome Scores of all aspects between the two groups (all P＞0.05). After the 3-week treatment, the Chinese Medical Syndrome Scores of the aspects of limbs tremor, stiff-neck, unstable walking, decreased physical activity, tongue manifestation, and pulse manifestation in the treatment group were lower than those in the control group (all P＜0.05). After the 3-week treatment, the total effective rate of the treatment group patients (96.00%) was higher than that of the control group patients (69.67%) (P＜0.05). Before the treatment, no statistically significant difference was found in the UPDRS total score and its various dimensions′ scores between the two groups (all P＞0.05). After the 3-week treatment, the UPDRS total score and its various dimensions′ scores in the treatment group were lower than those in the control group (all P＜0.05). There was no statistically significant difference in the incidence of adverse reactions during the treatment between the two groups (P＞0.05). ConclusionConventional western medicine combined with Guishao Roujing decoction + traditional Chinese medicine physical therapy in the treatment of Parkinson′s disease with liver blood deficiency pattern can effectively improve patients′ clinical symptoms and achieve evident clinical effects, without adding adverse reactions.