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药物与临床 | 更新时间:2015-10-13
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多定量指标研究千里香提取物工艺
Extraction of Murraya Paniculata (L.) Jack. by multiple quantitative indicators

内科 201401期 页码:73-75

作者机构:1广西壮族自治区中医药研究院,南宁市530022;2广西中药质量标准研究重点实验室,南宁市530022

基金信息:(收稿日期:2013-11-13修回日期:2014-1-19)
基金项目:广西科技厅科技攻关项目(桂科攻11107010-3-1)
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目的优选千里香药材乙醇提取物最佳工艺条件。方法以千里香醇提浸膏量、浸膏中九里香酮和5′-九里香酮的含量为考察指标,采用正交实验法对影响醇提工艺的主要因素:乙醇浓度、乙醇用量、提取时间和提取次数进行研究。结果千里香乙醇提取物提取最佳工艺为:用浓度为80%的乙醇提取,乙醇用量为药材量10倍,提取两次,每次1小时。结论该提取工艺方法可行、简便、合理。
ObjectiveTo screen the extracting method of ethanol in Murraya paniculata(L.) Jack. MethodsThe extraction process was optimized by orthogonal experiment with yield of ethanol extract, murrayone and 5′-murrayone as indexes ,and the concentration of ethanol, the ratio of solid to liquid, extraction time, and extraction times were used as the factors. ResultsThe optimum extracting condition was as follow: Murraya paniculata was extracted by 10 times of 80% EtOH for 2 times with 1 hour per time. ConclusionThe optimum extraction technology is feasible, simple and reasonable.
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