ObjectiveTo explore the effects of enteral nutrition support on immune function indexes and nutritional indexes in patients with severe acute pancreatitis. MethodsA total of 86 patients with severe acute pancreatitis were selected as research subjects and randomly divided into a control group or an observation group, with 43 cases in each group. The control group was given total parenteral nutrition support, while the observation group was given enteral nutrition support. The inflammation control, immune function indexes, nutritional indexes before and after treatment, as well as the prognosis were compared between the two groups. ResultsAfter 7 days of treatment, the serum levels of C-reactive protein, tumor necrosis factor-α and interleukin-6 in the observation group were lower than those in the control group, the peripheral blood levels of immunoglobulin A, immunoglobulin G, CD3+ and CD4+ in the observation group were higher than those in the control group; the serum levels of albumin and transferrin in the observation group were higher than those in the control group, while the Acute Physiology and Chronic Health EvaluationⅡ score and modified CT severity index score in the observation group were lower than those in the control group (all P＜0.05). ConclusionIn the treatment of patients with severe acute pancreatitis, enteral nutrition support can effectively control their inflammatory response, improve their immune function indexes levels and nutritional indexes levels, and further promote their prognosis.

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