ObjectiveTo investigate the clinical effect of exercise therapy in functional dyspepsia patients with anxiety and depression. MethodsEighty functional dyspepsia patients with anxiety and depression were selected and randomly divided into an observation group or a control group, with 40 cases in each group. Patients in the control group were treated with drug therapy, and patients in the observation group were treated with drug therapy combined with exercise therapy. The clinical efficacy of the two groups after 12 weeks of treatment was observed, and the Hamilton Depression Scale (HAMD) score, Hamilton Anxiety Scale (HAMA) score, Gastrointestinal Quality of Life Index (GIQLI) and serum gastrin-17 level were compared between the two groups before and after 12 weeks of treatment. ResultsAfter 12 weeks of treatment, the HAMD score, HAMA score, and serum gastrin-17 level in the observation group were lower than those in the control group, while the GIQLI and the total effective rate of treatment were higher than those in the control group (all P＜0.05). ConclusionExercise therapy combined with drug therapy in the treatment of functional dyspepsia patients with anxiety and depression can improve clinical symptoms, relieve anxiety and depression, and improve quality of life.

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