ObjectiveTo explore the association of cystatin C with in-stent restenosis after intracranial arterial stenting. MethodAccording to the results of cerebral digital subtraction angiography 6 months after surgery, 60 patients after intracranial arterial stenting were divided into a restenosis group or a non-restenosis group. Univariate analysis and multivariate logistic regression analysis were performed for the risk factors for in-stent restenosis after intracranial arterial stenting. ResultsSix months after surgery, a total of 16 patients developed in-stent restenosis, with an incidence of 26.7%. There was no statistically significant difference in gender, age, vascular stenosis severity, hemoglobin A1c level, smoking history, hypertension history, diabetes history, or coronary heart disease history between the two groups (all P＞0.05). The proportion of patients with dyslipidemia in the restenosis group was higher than that in the non-restenosis group (P＜0.05). Six months after surgery, the cystatin C level in the restenosis group increased as compared with that before surgery and was higher than that in the non-restenosis group (all P＜0.05). The results of multivariate logistic regression analysis showed that an abnormal level of cystatin C and dyslipidemia were risk factors for in-stent restenosis after intracranial arterial stenting (all P＜0.05). ConclusionAn abnormal level of cystatin C and dyslipidemia are independent risk factors for in-stent restenosis after intracranial arterial stenting.

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