ObjectiveTo investigate the effect of jejunal enteral nutrition support combined with microecologics in the treatment of patients with severe acute pancreatitis. MethodsA total of 32 patients with severe acute pancreatitis were selected and randomly divided into a conventional group or an experimental group, with 16 cases in each group. The conventional group was given routine treatment and jejunal enteral nutrition support, based on which the experimental group was treated with microecologics, and both groups were treated continuously for 1 week. The clinical efficacy, serum indexes, quality of life, and intestinal flora of patients in the two groups were compared. ResultsBefore treatment, there was no statistically significant difference in serum amylase, procalcitonin, or creatinine level between the two groups, nor was there in the intestinal number of Enterobacteriaceae, Enterococcus, Bifidobacterium, or Lactobacillus (all P＞0.05). After 1 week of treatment, the total effective rate of treatment in the experimental group was higher than that in the conventional group, the serum levels of amylase, procalcitonin, and creatinine, as well as the intestinal numbers of Enterobacteriaceae and Enterococcus, were lower than those in the conventional group; the score of the 36-Item Short Form Health Survey on each dimension and the intestinal numbers of Bifidobacterium and Lactobacillus in the experimental group were higher than those in the conventional group (all P＜0.05). ConclusionJejunal enteral nutrition support combined with microecologics can effectively improve the quality of life for patients with severe acute pancreatitis, reduce their their inflammatory factors levels, and regulate intestinal flora.

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