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长春西汀联合丹红注射液治疗急性脑梗死的疗效及对患者神经功能等的影响
Efficacy of vinpocetine combined with danhong injection and its impact on neurologic function in patients with acute cerebral infarction

内科 201505期 页码:623-625

作者机构:甘肃省定西市第二人民医院,定西市743000

基金信息:(收稿日期:2015-06-27修回日期:2015-08-04)

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2015.05.09

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目的探讨长春西汀联合丹红注射液治疗急性脑梗死患者的效果及对患者神经功能等的影响。方法选取2013年1月到2014年1月住院治疗的急性脑梗死患者100例作为研究对象,随机分为观察组和对照组,每组50例。两组患者均予常规治疗,在此基础上对照组患者予长春西汀治疗,观察组患者给予长春西汀以及丹红注射液治疗,观察比较两组患者的临床治疗效果,以及治疗前后两组患者NIHSS评分、血浆黏度、红细胞压积、纤维蛋白原水平的变化。结果观察组患者治疗总有效率为96.0%,对照组治疗总有效率为78.0%,两组比较差异具有统计学意义(P<0.01);观察组患者临床疗效优于对照组患者(P<0.01)。治疗后观察组患者NIHSS评分显著低于对照组患者,两组比较差异具有统计学意义(P<0.01)。治疗后两组患者的血浆黏度、红细胞压积、纤维蛋白原均较治疗前显著降低(P<0.05);且观察组患者的血浆黏度、红细胞压积、纤维蛋白原水平显著低于对照组,差异具有统计学(P<0.05)。结论长春西汀联合丹红注射液治疗急性脑梗死患者可提高疗效,促进患者神经功能的恢复,降低血黏度,值得临床推广和应用。
ObjectiveTo investigate the efficacy of vinpocetine combined with danhong injection and its impact on neurologic function in patients with acute cerebral infarction. MethodsFrom January 2013 to January 2014, 100 hospitalized patients with acute cerebral infarction were selected and randomly divided into observation group and control group with 50 patients in each. Both groups were given conventional treatments. Patients in the control group were added with Vinpocetine, while patients in the observation group with both vinpocetine and danhong injection. The clinical efficacy of the two groups and the changes of NIHSS score, plasma viscosity, red blood cell hematocrit, and fibrinogen level before and after treatment were observed. ResultsThe total effective rates of the observation group and the control group were 96% and 78.0%, respectively (P<0.01). There were significant differences between the two groups(P<0.05). The clinical efficacy of the observation group was superior to that of the control group (P<0.01). After treatment, the NIHSS scores of the observation group were greatly lower than that of the control group, which had significant differences. The plasma viscosity, red cell pressure volume, and fibrinogen level of the both groups decreased obviously after treatment, especially in the observation group, and there were significant differences between the two groups (P<0.01). ConclusionsVinpocetine combined with danhong can improve the efficacy, promote the recovery of neurological function, and reduce the blood viscosity of acute cerebral infarction, which is worthy of clinical promotion.
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