内科

目的探讨蚓激酶联合阿托伐他汀对急性脑梗死患者颈动脉斑块的影响。方法将脑梗死患者100例随机分为观察组和对照组，对照组患者采用阿托伐他汀治疗，观察组采用蚓激酶联合阿托伐他汀治疗，通过彩色多普勒超声检查比较两组患者治疗前后颈动脉粥样硬化斑块的变化，检测比较两组患者血浆纤维蛋白原及血脂水平。结果治疗6个月后，观察组患者血浆纤维蛋白原、TG、TC、LPL-C均显著降低；治疗后的颈动脉斑块大小、厚度和IMT与治疗前及对照组比较，差异均有统计学意义（P＜0.05）。结论蚓激酶联合阿托伐他汀能明显改善急性脑梗死患者的颈动脉斑块。

ObjectiveTo explore the effect of lumbrokinase coupled with atorvastatin on carotid plaque in patients with acute cerebral infarction.Methods100 patients with acute cerebral infarction were randomly divided into observation group and control group.Patients in the control group were treated with atorvastatin,while patients in the observation group with atorvastatin and lumbrokinase.Color Doppler ultrasonography was used to test carotid plaque before and after treatment.Levels of plasma fibrinogen and serum lipid in the two groups were measured.ResultsIn the treatment group,the serum levels of serum fibrinogen,TG,TC,and LPL-C were all significantly lower in 6 months after treatment than those before treatment.Size and thickness of the carotid plaque and IMT were statistically different compared with those before treatment or those in the control group (P＜0.05).Conclusion Combination of Lumbrokinase and Atorvastatin significantly improve carotid plaque in patients with acute cerebral infarction.

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