ObjectiveTo investigate the clinical features of mantle cell lymphoma(MCL) and analyse the clinical data of MCL patients with bone marrow involvement. MethodsThe clinical features of 21 patients with MCL in our hospital were retrospectively analyzed. Age of onset,LDH,β2 microglobulin,leukocytes and overall survival time of patients with or without bone marrow involvement were compared. ResultsOf the 23 patients,there were 15 males and 6 females,including 17 cases at clinical stage Ⅲ-Ⅳ and 10 cases with bone marrow involvement.The median age was 55 years. There was no significant difference in age of onset,LDH,β2 microglobulin, leukocytes and other parameters (P＞0.05). The overall survival time of them were (23.4±4.2) and (72.6±15.4) months respectively,showing a significant difference(P=0.035). ConclusionMCL patients with bone marrow involvement have a shorter survival time.

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